Termination of inflammation.

Termination of inflammation.

Termination of inflammation. Like congestion, inflammation may terminate by resolution. In this case the exuded lymph undergoes chemical change, and the products are absorbed and carried off by the blood vessels and lymphatics, to be thrown out of the body by the kidneys, liver, the glands of the skin, and the other excretory organs. The cells, which have wandered into the neighboring tissues from the blood vessels, gradually disappear or become transformed into fixed cells. Those which are the result of the tissue cells, wakened into active life, follow the same course. The vessels themselves contract, and, having resumed their normal caliber, the part apparently reassumes its normal condition; but it is always weakened, and a new inflammation is more liable to reappear in a previously inflamed part than in a sound one. The alternate termination is necrosis, or mortification. If the necrosis, or death of a part, is gradual, by small stages, each cell losing its vitality after the other in more or less rapid succession, it takes the name of ulceration. If it occurs in a considerable part at once, it is called gangrene. If this death of the tissues occurs deep in the organism, and the destroyed elements and proliferated and dead cells are inclosed in a cavity, the result of the process is called an abscess. When it occurs on a surface, it is an ulcer, and an abscess by breaking on the exterior becomes then also an ulcer. Proliferating and dying cells, and the fluid which exudes from an ulcerating surface and the débris of broken-down tissue is known as pus, and the process by which this is formed is known as suppuration. A mass of dead tissue in a soft part is termed a slough, while the same in bone is called a sequestrum. Such changes are especially liable to occur when the part becomes infected with microorganisms that have the property of destroying tissue and thus causing the production of pus. These are known as pyogenic microorganisms. There are also bacilli that are capable of multiplying in tissues and so irritating them as to cause them to die (necrose) without forming pus.